ACE Extended Cancer Panel for RNAmckinleymedia
The ACE Extended Cancer Panel for RNA provides unparalleled detection of unique variant types that are not identifiable by DNA sequencing analysis alone. The assay identifies gene expression levels, gene fusions, SNVs and indels in over 1,400 cancer-associated genes. This panel enables extensive gene fusion discovery of both clinically actionable* fusions involving critical genes such as ALK, ROS1, RET, and novel fusions involving other targeted genes that might be missed with DNA analysis alone.
Personalis’ targeted approach to RNA sequencing provides researchers with higher quality RNA results compared to those achieved by conventional transcriptome sequencing practices. We accomplish this by focusing only on genes related to cancer biology (by excluding intronic RNA from unspliced transcripts) and by using a capture method that can isolate degraded RNA better than other methods. This results in higher quality RNA reads with minimized background.
2x 125 bp
|Sample source||FFPE, fresh frozen, fine needle aspirates, PBMCs|
|Analysis configuration||Tumor only|