Introduction to Liquid Biopsies

Maik M. Pruess, PhD
Sr. Field Application Scientist

The liquid biopsy is a relatively new concept that has gained traction over the last several years. Circulating tumor DNA (ctDNA) fragments are released by tumor cells into the blood, and contain genetic alterations that reflect the tumor tissue from which they originate. While a tumor tissue biopsy is often invasive and costly, the liquid biopsy serves as a simple, non-invasive alternative to interrogate the tumor mutational landscape in serial fashion, and can be used in a variety of both research and clinical applications. NeXT Liquid Biopsy™ is a first-of-its-kind, high performance exome-wide liquid biopsy assay to further enhance the development of more efficacious cancer therapies in advanced solid tumor indications.