Comprehensive immunogenomic characterization

ImmunogenomicsID™, the latest analytics component of the ACE ImmunoID platform, summarizes critical areas of tumor biology such as the antigen processing machinery (APM), human leukocyte antigens (HLA), checkpoint modulation, and tumor escape.

ImmunogenomicsID combines exome and transcriptome sequencing data from a paired tumor and normal sample to generate a comprehensive immunogenomic profile of the tumor and its microenvironment. This includes tumor mutational burden (TMB) and reporting on gene-level expression (TPM), variant type (SNVs, indels, fusions), variant expression, DNA and RNA allelic fraction (>5%), HLA Class I somatic mutation variant calls, as well as population database searches.