Blog

29 Nov, 2022

Tumor microenvironment: An Emerging Space in Cancer Theranostics

Thane Natarajan, PhD Senior Product Manager, Biomarker Discovery Tumor microenvironment: An Emerging Space in Cancer Theranostics Introduction The tumor microenvironment (TME) has long been known to play a central role in tumor progression and immune evasion. An established tumor generally resides in a complex microenvironment (Fig. 1) which nests [...]

26 Oct, 2022

When You’re One in a Million, It Gets Personal.

Jane Antony, PhD Field Application Scientist When You’re One in a Million, It Gets Personal. Interesting metaphor. We’re perfectly imperfect designs. ― Nina Riggs, The Bright Hour: A Memoir of Living and Dying Cancer, which mirrors Virchow’s principle of Omnis-cellulae-e-cellulae (all cells come from cells), is a disease that arises [...]

16 Aug, 2022

What’s Next After MRD?

John West Chief Executive Officer Q&A with John West, Founding CEO of Personalis What's Next After MRD? Personalis has been building and innovating for more than a decade, but we believe we’ve only just begun. In this multipart series, we have been talking to Personalis’ founder and CEO, [...]

1 Aug, 2022

Leading the Way in Whole Human Genome Sequencing, Including for Cancer MRD

John West Chief Executive Officer Q&A with John West, Founding CEO of Personalis Leading the Way in Whole Human Genome Sequencing, Including for Cancer MRD When Personalis was founded in 2011, technological advances had just brought whole genome sequencing into reach, opening the possibility to improve patient outcomes. This [...]

15 Jun, 2022

What Does the Future Hold for Liquid Biopsy Technology

Maik Pruess, PhD  Senior Field Applications Scientist What Does the Future Hold for Liquid Biopsy Technology? Liquid biopsy is a fascinating and quickly evolving technology. Since the early 2000s, these tests have become increasingly complex, capable of gathering data on tens of thousands of genes across a patient’s DNA [...]

8 Jun, 2022

Liquid Biopsies: A Technical Dive into Biology and Innovations

Travis J. Yates, PhD  Field Applications Scientist Liquid Biopsies: A Technical Dive into Biology and Innovations If you’ve been following our series thus far, you’ve learned that while new and innovative strategies to combat the progression of malignant disease continue to evolve, the field has an unmet need. The [...]

3 Jun, 2022

How variant-specific shedding may be key for ctDNA test interpretation

Lee McDaniel, MD, MSE Sr. Bioinformatics Scientist How variant-specific shedding may be key for ctDNA test interpretation In a study led by University of Pennsylvania and the Parker Institute for Cancer Immunotherapy, Personalis is a co-author on a poster being presented at the American Society of Clinical Oncology (ASCO) [...]

23 May, 2022

An Introduction to the Personalis Liquid Biopsy Approach

Kedar Hastak, MS, PhD Manager, Field Applications Scientist An Introduction to the Personalis® Liquid Biopsy Approach As oncology technology continues to improve, there is an ever-growing buzz surrounding the topic of liquid biopsies. Just on its own, the concept itself is captivating: instead of having to take a physical sample [...]

11 May, 2022

How Liquid Biopsy Technology is Changing What’s Possible in Cancer Treatment

Erin Newburn, MS, PhD Sr. Director, Field Applications Scientist How Liquid Biopsy Technology is Changing What's Possible in Cancer Treatment There’s no doubt that early detection is essential for good outcomes when dealing with cancer treatment, and this is equally true when detecting disease recurrence. Patients who have already undergone [...]

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