Blog
ACE ImmunoID Platform for reverse translation
December 12th, 2017
by: Christelle Johnson, MS, PhD
Laboratory models have been central to the fast evolving field of immuno-oncology and immunotherapy drug development. We continue to learn from ...READ MORE
Ethnic disparities in precision genomics
November 29th, 2017
by: Erin Newburn, MS, PhD
The premise of the right drug for the right patient at the right time is critical for indications from cardiovascular and infectious disease to the latest immuno-oncology strategies. It’s imperative to comprehend which patient will derive benefit from ...READ MORE
Refining neoantigen load
October 30th, 2017
by: Erin Newburn, MS, PhD
Tumor mutational burden (TMB) has now been established as a positive predictive biomarker of response to immune checkpoint inhibitors with more studies demonstrating correlations between the overall mutational landscape and clinical benefit ...READ MORE
Overcoming the obstacles of neoantigen identification
October 11th, 2017
by: Sean Michael Boyle, MS, PhD Erin Newburn, MS, PhD |
Neoantigen-based cancer vaccines represent new, truly personalized therapeutic approaches to treating cancer.READ MORE
Resistance to immunotherapy: The elusive routes of immune escape
August 22nd, 2017
by: Erin Newburn, MS, PhD
Achieving a durable clinical response is the ultimate goal in immuno-oncology clinical trials. With immunotherapies showing long-lasting, unprecedented responses in cancer indications such as melanoma and Non-Small Cell Lung Cancer (NSCLC), these immune-boosting drugs seem to be displaying genuine advancesREAD MORE