Can gene and variant expression from RNASeq be done well using FFPE specimens?

As immunotherapy translational research studies using RNA data provide new clues to patient response, identifying the upfront technical factors affecting success is vital.READ MORE

The power of gene and variant-level expression in immuno-oncology biomarker discovery

Recent advancements in RNASeq technology have revolutionized the search for the genes and gene expression signatures that determine immunotherapy response by providing a high throughput method of comprehensively examining changes in these functional elements.READ MORE

ACE ImmunoID Platform for reverse translation

Laboratory models have been central to the fast evolving field of immuno-oncology and immunotherapy drug development. We continue to learn from ...READ MORE

Ethnic disparities in precision genomics

The premise of the right drug for the right patient at the right time is critical for indications from cardiovascular and infectious disease to the latest immuno-oncology strategies.  It’s imperative to comprehend which patient will derive benefit from ...READ MORE

Refining neoantigen load

Tumor mutational burden (TMB) has now been established as a positive predictive biomarker of response to immune checkpoint inhibitors with more studies demonstrating correlations between the overall mutational landscape and clinical benefit ...READ MORE