tward

Toby Ward, PhD

About Toby Ward, PhD

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4 Oct, 2016

The importance of proper formalin fixation of FFPE specimens

Tumor biopsies are often formalin-fixed and paraffin-embedded (FFPE) for histological staining and archival purposes. Formalin treatment preserves tissue, but also damages nucleic acids and poses a challenge to identifying true variants in tumor samples using next-generation sequencing (NGS).