Christelle Johnson, MS, PhD Senior Field Applications Scientist Cancer Genomics & Immuno-Oncology Neoantigen-based cancer immunotherapies We are witnessing one of the most accelerated scientific efforts in response to the COVID-19 pandemic. Among these efforts that include sequencing the virus, designing the very first prophylactic vaccines, conducting clinical trials, demonstrating efficacy, [...]
Comprehensive Immunogenomics Profiling for the Discovery of the Next Generation of Oncology Biomarkers
Christelle Johnson, MS, PhD Senior Field Applications Scientist Cancer Genomics & Immuno-Oncology Comprehensive Immunogenomics Profiling for the Discovery of the Next Generation of Oncology Biomarkers Although hypothesized back in the early 1900s that the immune system may provide a protective mechanism against tumorigenesis, only recently have the fields of immunology [...]
Laboratory models have been central to the fast evolving field of immuno-oncology and immunotherapy drug development. We continue to learn from ...
Improved understanding of the cancer-immunity cycle has provided the basis for novel immunotherapeutic approaches. Individual therapeutic agents designed to intervene at different stages of the cycle have shown significant promise .
Christelle Johnson, MS, PhD Field Applications Scientist Genomics at the core of cancer immunotherapy efficacy We owe much of the progress in cancer immunotherapy to the understanding of basic science. Decades of research have helped establish hallmarks of cancer, which include a complex battle between oncogenes and tumor suppressor genes [...]