Biomarkers US: October 3-4, 2022

Presentation

Jane Antony

Tuesday, October 4 | 9:50 am – 10:20 am PDT

Presenter: Jane Antony, PhD
Field Application Scientist

Personalis NeXT Platform:
Enabling the future of precision oncology with comprehensive, unprecedented tumor profiling solutions for both tissue and liquid biopsy

Description:

  • Combining highly sensitive, exome-scale DNA and RNA sequencing with advanced analytics, ImmunoID NeXT™ provides a multidimensional view of the tumor and the tumor microenvironment from a single tumor sample preparation
  • A clinical case study in a cohort of late-stage melanoma patients demonstrating how the integration of neoantigen burden, HLA LOH, and Antigen Presentation Machinery (APM) mutational data formed a composite biomarker that more accurately predicted response to checkpoint blockade than other markers
  • In parallel, specimens may be processed using NeXT Personal™, an ultrasensitive tumor-informed liquid biopsy assay, designed to detect molecular residual disease and cancer recurrence at the earliest timepoints, with simultaneous variant tracking for additional insight into disease progression

2022 Biomarkers US, October 3-4