Genome, Transcriptome, and Additional Services
Ideal for researchers seeking the most comprehensive and accurate genome, transcriptome, and other services for human genomic research.
Whole Genome Sequencing (WGS) and Analysis
Whole Genome Sequencing is performed on Illumina® platforms with a minimum of 2 x 100 paired reads. Sequence data is aligned and variants are called and annotated using the Personalis advanced variant discovery and annotation engine. Read more about the Personalis ACE Platform™.
- 30x WGS
- Whole Genome Sequencing using Illumina TruSeq™ chemistry. Average of 30x coverage of more than 90% of the genome (>110 Gbp).
- 60x WGS
- Whole Genome Sequencing using Illumina TruSeq chemistry. Average of 60x coverage of more than 90% of the genome (>220 Gbp).
- WGS AnalysisOnly
- For customers with existing whole genome data, we can utilize our advanced variant calling and annotation capabilities to extract the best results from your data.
RNA-Seq is performed on Illumina platforms with a minimum of 2 x 100 paired reads (25 or 50 million reads).
Nucleic Acid Extraction
Personalis laboratory personnel have extensive experience working with many sample types, including blood, saliva and FFPE (formalin-fixed paraffin-embedded) samples. We routinely work with customers to get the optimal results from challenging samples.
Biomedical Analysis and Interpretation
In addition to comprehensive variant annotations, Personalis can provide interpretive research reports for a wide variety of study types (from large case control studies to proband or family studies) and study areas (common disease, Mendelian disease, pharmacogenomics, and cancer). Our analyses benefit from the robust upstream sequencing, alignment, and variant calling technologies, in addition to the comprehensive variant annotations we employ.
Research Study Design
Personalis’ Ph.D. scientists can assist you with study design, including power calculations, sample selection, identification of matched controls, and analysis plan. We can work with you on a variety of study types, and provide the level of support needed for you to accomplish your research objectives.