Go Beyond the Standard Exome
Personalis® ACE Exome™ for Discovery Research offers the most up-to-date and comprehensive exome coverage of any commercially available service. Based on the ACE Platform™ our end-to-end research service solution is ideal for researchers seeking the most comprehensive and accurate, yet cost-effective results.
The Personalis ACE Exome for Discovery Research
augments a standard exome by supplementing
coverage of over 8,000 genes of known biomedical
importance, enabling variants to be identified more
accurately and reliably in these regions. The ACE Exome also
provides coverage of regions outside the exome, including ~12,000 regulatory regions and ~25,000 functionally important intergenic regions, e.g., those associated with disease or highly conserved across species. This highly accurate and sensitive assay has a footprint of ~93MB, the broadest and most optimized exome platform available for research.
Broadest, most optimized exome platform available for research
ACE Exome focuses on sensitivity and specificity vs. average depth to maximize true variation detection.
Maximizing Variant Detection
ACE Exome for Discovery Research has been optimized to provide the maximum number of biomedically relevant or high-value variants for your project with an average of 3.5 to 6 Gigabase (Gb) of sequencing per sample. We maximize the number of high-value variants for your research project by incorporating the following three approaches: